Okay they are in the cell so what? The spike protein churned out by the bodys cells in response to the mRNA contain a fully-functional s1 binding sub-unit and RBD. Those instructions tell the cell to make spike proteins. 27 apr 2021. In fact, recent studies show breastfeeding after vaccinations may provide babies with protection. Every cure has a starting point. My assumption is that it depends on the number of virus particles the person receives within a certain period.If you get in a close contact with someone who has already contracted the virus and spend hours together (like in a hospital room or a small office) theres a high chance for both to replicate and exchange the virus back and forth more and more exponentially and overloading your bodies before their immune systems respond. Ogata, Alana, et al.Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients. Clinical Infectious Diseases. Two of the earliest vaccines approved in the US were delivered by Moderna and Pfizer-BioNTech. A lot of people think of it as a respiratory disease, but its really a vascular disease, says Assistant Research Professor Uri Manor, who is co-senior author of the study. Preprint Authors Most of them have appeared in countries with multiracial populations, though. The, , called 2P, as in two proline molecules, is, No Evidence Vaccine-Generated Spike Protein Is Harmful, prepared in response to the attention brought by the interview, Bridle says the Canadian government should be called upon to immediately halt the mass vaccination program of children and adolescents. He says there is no immediate threat of severe COVID-19 in the majority of Canadian children and adolescents, and that more safety and efficacy data is needed for the use of experimental vaccines., the use of the Pfizer/BioNTech COVID-19 vaccine in children 12 to 15, following authorization of the vaccine in youth 16 years old and older in December. Safety of COVID-19 Vaccines. CDC.gov. In these cases, limiting damage and supporting affected organssuch as with drugs that manipulate normal metabolism and repair processesis paramount. 1s Proposal on Voter Rolls. COVID, on the other hand, is known to have significant effects on many tissues and organs, he said. If a burgler, theoretically, is born inside your house and cannot get out alive and is killed by the residents, there is no damage and no damage in the future at other houses. Any protein in the blood will get concentrated in breast milk, he said on the radio show. Heres a step-by-step guide to how they work. The majority of people wouldnt even know they had covid. I am familiar only in part with some of the details you explain.I wonder in the optimistic scenario, which I want to believe, then what triggered the not to many but enough to ask cases of thrombocytopenia? Most, if not all of you people are idiots you just want to be heard and want to rant pseudoscience, and no where remotely close. proteins and the development of COVID-19. But recent studies in animals and cultured cells have found . Lonely Hearts at Risk: Lifelong Bachelors Face Dire Prognosis With Heart Failure, Galactic Explosion Reveals New Details About the Universe, New Technology Can Detect Cancer Cells Without Invasive and Expensive Surgery, Chemotherapy Chaos: Tumor Cells Response to Treatment Is Driven by Randomness, Chunky Dunk? 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The spike protein is not pathogenic. Every cell invaded by the vaccine mRNA will eventually be destroyed by the immune system releasing spike protein. structures of the SARS-CoV-2 virus, together with proprietary How the mRNA vaccines work to fight COVID-19. 10 June 2021. 30 Mar 2021. vascular wall thickening the hallmark of Pulmonary artery hypertension. In addition, the Food and Drug Administration inspects vaccine production facilities and reviews manufacturing protocols to make sure vaccine doses are of high-quality and free of contaminants. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal modelproving that the spike protein alone was enough to cause disease. But theres absolutely no harm. We thus hypothesised that SARS-CoV-2 could use the ACE2 receptor to infect a range of nonhuman, non-bat hosts. Your support will accelerate the pace of breakthroughs in understanding disease and pave the way to new drug therapies. There is some evidence that the spike proteins generated by the Moderna Covid-19 vaccine leave the site of injection. The cells genetic machinery reads the mRNAs instructions, and any leftover mRNA is ultimately destroyed by the cell. However, vaccine-generated spike proteins cant do that fusion because they are locked in the pre-fusion shape. COVID-19 Vaccines While Pregnant or Breastfeeding. Similarly, scientists studying other coronaviruses have long suspected that the spike protein contributed to damaging vascular endothelial cells, but this is the first time the process has been documented. Email sent to FactCheck.org. Furthermore, the study concludes that vaccines not only protect people from SARS-CoV-2 infection, but also from damage to the endothelium, a thin membrane that lines the inside of the heart and blood vessels. In the radio interview with Pierson, Bridle says he and other international collaborators obtained the document through a request for information to a Japanese regulatory agency, claiming that it shows for the first time ever where the mRNA vaccines go after vaccination.. LA JOLLA, CA Scientists at Scripps Research have obtained high-resolution, atomic-scale details of the structure of a SARS-CoV-2 "spike" protein from an experimental COVID-19 vaccinedetails that are consistent with the robust neutralizing antibody responses the vaccine elicited in preclinical and phase 1 clinical studies. WHAT WE FOUND "The bottom line is the vaccine spike. The researchers next hope to take a closer look at the mechanism by which the disrupted ACE2 protein damages mitochondria and causes them to change shape. THUS VIRUSES WERE CREATED WITH CERTAIN INTELLIGENCE IN THE PHYSICAL ENVIRONMENT. Similarly, scientists studying other coronaviruses have long suspected that the spike protein contributed to damaging vascular endothelial cells, but this is the first time the process has been documented. Bryam Bridle profile. Science. The spike also activates CD4 and CD8 T cells from anywhere beyond 70% of COVID-19 patients . An open space or just an open window could reduce the virus transmission. breastfeeding after vaccinations may provide babies with protection. SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2, Yuyang Lei, Jiao Zhang, Cara R Schiavon, Ming He, Lili Chen, Hui Shen, Yichi Zhang, Qian Yin, Yoshitake Cho, Leonardo Andrade, Gerald S Shadel, Mark Hepokoski, Ting Lei, Hongliang Wang, Jin Zhang, Jason X-J Yuan, Atul Malhotra, Uri Manor, Shengpeng Wang, Zu-Yi Yuan, and John Y-J Shyy, Office of Communications Must I, as an American citizen, be fully vaccinated to transit through the Frankfurt airport from Slovenia on my return to Chicago? Accessed 29 June 2021. So they are designed to migrate and attach on the outside of that cell so the cells in the immune system can notice them and create antibodies. The Salk Institute proves this assumption to be dangerously inaccurate." (source) Can this Newly Manufactured Synthetic Spike Protein Be Transmitted to the Unvaccinated? Theres been a growing consensus that SARS-CoV-2 affects the vascular system, but exactly how it did so was not understood. Vaccination is a calculated risk and with tried and true vaccines the risks are very rare, but no vaccine is safe in that deaths and injuries occur due to allergies, negligence and medical incompetence. Some immune cells latch onto the spikes and produce antibodiesY-shaped molecules that will recognize spike proteins and block them from getting inside other cells. Im a layman but I think I got it.The damage happens when a free spike protein binds to a cell. They travel extensively through the lymph system and a large number end up in the spleen. Other parts of the immune system such as killer Tcells will destroy the spike protein infected cell with its exterior attached spike protein. This research goes against all cellular biology. And it is located upon a plateau. Spikes and spike protein fragments move to the outside of the cell and protrude from the surface where they will be recognized by the immune system. 03 In a separate study, in collaboration with pulmonary Salk Institute expands research to find treatments and cures for COVID-19 14 June 2021. BUT: Then the immune system will destroy that cell (also some brain cells which will not regenerate). . 4 June 2021. Professor Greg Lemke is delving into how receptors regulate the immune response and is studying ways to prevent the cytokine storms that develop in COVID-19, as the body produces such an overwhelming immune response in the lung that the collateral damage can be lethal for patients. For more, see How safe are the vaccines?. Spikes created inside cells from mRNA are degraded before they exit the cell through the MCH mechanism and the result it the standard immune system hand off is made to fully consume and degrade these protein peptides. Vol. We are slowly getting to the right conclusion. In reality, the jury is still out which is why these are approved for emergency use, not FDA approved in the usual (years long) tradition. COVID-19 Vaccine Research at U of G Awarded Provincial Funding. Bryam Bridle profile. COVID vaccines and breastfeeding: what the data say. Nature. website there is limited data available on the safety and the effects of vaccination in lactating people or breastfed babies because the clinical trials didnt include people who were breastfeeding. MYTH: The COVID-19 vaccine can affect women's fertility. Possibly an end-of-life vascular event. Show the data which proves a healthy 10 year old is 50000 times more likely to die from covid 19 vs a vaccine. As weve reported, the Vaccine Adverse Event Reporting System is designed to detect potential problems thats why its there but it does not show whether the vaccines caused any of the reported issues. if and how long-term immunity can be established. who would not be expected to be at high risk from COVID-19 itself. Salk News - Vaccine protects COVID-19 survivors against variants; virus' spike Even if breaks from the enzymes which tell your immune system not to get rid of the useless mrna the body will most likely just get rid of the mrna. I think, adverse effects of the vaccine happen more often if the needle hits near a bigger blood vessel in the muscle. The research was supported by the National Institutes of Health, the National Natural Science Foundation of China, the Shaanxi Natural Science Fund, the National Key Research and Development Program, the First Affiliated Hospital of Xian Jiaotong University; and Xian Jiaotong University. 02 In addition, Izpisua Belmonte led a team of multi-institution scientists to develop a new viral screening test that can not only diagnose COVID-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruseslike influenzathat might be mistaken for the coronavirus. While the findings themselves arent entirely a surprise, the paper provides clear confirmation and a detailed explanation of the mechanism through which the protein damages vascular cells for the first time. inhibitory factor) plays a role in pancreatic cancer. Jason McLellan, a structural biologist at the University of Texas at Austin who has been studying spike proteins in other coronaviruses for years and whose work was fundamental for the development of COVID-19 vaccines, said Bridles statements are not correct. from replicating in the body, thereby reducing the severity Research Professor Margarita Behrens is researching the effects of virus-induced maternal immune activation on brain development of offspring, which, given the number of COVID-19 infections worldwide, could reveal a significant effect. LA JOLLAScientists have known for a while that SARS-CoV-2s distinctive spike proteins help the virus infect its host by latching on to healthy cells. It is now known that many of the toxid effects of being infected by SARS COV 2 stem directly from the spike protein ie the spike protein itself is a pathogen. Accessed 29 June 2021. Theres been a growing consensus that SARS-CoV-2 affects the vascular system, but exactly how it did so was not understood. See: https://pubmed.ncbi.nlm.nih.gov/33053430/ and https://pubmed.ncbi.nlm.nih.gov/33328624/, In Israel, where vaccination rates are much higher, myocarditis cases are under review for possible association with vaccination. Their pipeline Retweeted. Vaccines that trigger spike protein production only affect a very limited number of cells, as the genetic material that these vaccines contain does not auto-replicate in the body. 6. The authors believe that this is good news with regard to the vaccines currently in circulation; they may be right. See: https://www.regulations.gov/document/FDA-2020-N-1898-0246. New COVID-19 booster vaccine offers high level of protection in mice This binding disrupted ACE2s molecular signaling to mitochondria (organelles that generate energy for cells), causing the mitochondria to become damaged and fragmented. And so theres no risk of transmission through the breast milk. This is because the spike parts are displayed on the cell. Its very safe, says WHOs Chief Scientist Dr. Soumya Swaminathan on a podcast produced by the organization. PDF New COVID-19 booster vaccine offers high level of protection in mice I wonder what this means for spike protein vaccine safety. He posted a good link. Ivermectin, hydroxychloroquine, and chloroquine are especially important in preventing new binding of the spike protein to the ACE2 receptors that need to be bound in order for either the spike protein alone or for the entire virus to gain entry into the target cells ( Lehrer and Rheinstein, 2020; Wang et al., 2020; Eweas et al., 2021). On Point with Alex Pierson. Global News Radio. The Pfizer/BioNTech and Moderna vaccines carry instructions to produce a variant of the spike protein that has been locked into whats called a prefusion-stabilized conformation. (See our Email Privacy Policy for details.) believes that immune cells called memory B and T cells We discuss the paper, the authors' clarification. Anyone can submit a report to VAERS for any health problem that occurs after an immunization. Canceling the Spike Protein: Striking Visual Evidence - Orthomolecular.org 10 June 2021. What was claimed. shows that SARS-CoV-2's "distinctive 'spike' protein . However, the websites are also saying all travelers must be fully vaccinated to depart from Frankfurt. It must first be understood by all. There is no screening or vetting of the report and no attempt to determine if the vaccine was responsible for the problem. Burnham Prebys Medical Discovery Institute, Pao will develop Only small fragments of the ubiquoitim proteosome protein degradation process of the induced spike protein are presented on the surface of the cell by the MHC 1 ANTIGEN presentation system. The spike protein, particularly the RBD, is therefore the main antigenic target for vaccine formulation. Because the vaccine produced spike proteins are locked into this state, they cannot properly bind to the ACE2 receptors in other, healthy cells. The Spike of SARS-CoV-2: Uniqueness and Applications Kelly, Jeannie. Home - Science - Research - Coronavirus Research. It is not a toxin, McLellan told us in an email. University of Guelph. The spike protein generated by a Covid-19 vaccine can leave the site of injection and enter the bloodstream, which could possibly be causing deaths and vaccine injuries. 01 Professor Juan Carlos Izpisua Belmonte is collaborating with This is how they escape without being torn to pieces. The premise of this study is the Spike proteins are attaching to the epithelial cells that line our circulatory system. I am reading and learning from the comments and knowledge above. The Institute is an independent nonprofit organization and architectural . synthetic virology and chemical biology platforms, to create Would these vaccines not cause similar harm? https://youtu.be/9EfToFXwx98?t=479. COVID-19 vaccine for children. Statement, Canadian Paediatric Society. So the spike proteins dont need to exit the cells and they dont need to bind to new cells. 2021 Oct 13;2021.10.12.464152. doi: 10.1101/2021.10.12.464152. When either Sars-CoV-2 or HIV infects a person both viruses only cause an innocuous flu-like infection but like HIV, the Sars-CoV-2 spike protein can linger in the body attacking the T cells of the immune system. Jonas Edward Salk (/ s l k /; born Jonas Salk; October 28, 1914 - June 23, 1995) was an American virologist and medical researcher who developed one of the first successful polio vaccines.He was born in New York City and attended the City College of New York and New York University School of Medicine.. Yes, it's true that the spike protein with the N-protein, will not replicate. COVID-19 Vaccines and Children: A Scientists Guide for Parents. Canadian Covid Care Alliance. COVID-19 Vaccine Research at U of G Awarded Provincial Funding. Ontario Veterinary College website. However, it says, based on available data COVID-19 vaccines are thought not to be a risk.. But Science proves as well as they are proof of INTELLIGENCE EXISTENCE. The spike protein vaccine with the 2P mutation . Bret Weinstein | DarkHorse Podcast: #79: #NotAllMice (Bret - Apple In reality, Covid-19 is BOTH a vascular and a respiratory disease. influenza and now COVID-19, will collaborate with The Your partnership allows our scientists to accelerate the pace of high-risk, high-reward discoveries that have the potential to benefit the health of all humanity-be it cancer, Alzheimers disease, climate change, infectious diseases or more.